FRAT Test - Advanced Early Detection for Brain Folate Issues

The Folate Receptor Autoantibody Test (FRAT) is a breakthrough blood test that identifies autoantibodies which block the transport of folate (Vitamin B9) to the brain. When detected early, families and healthcare providers can take action that may help support better neurological development and long-term brain health.

Sample Type

What's included

The Folate Receptor Autoantibody Test (FRAT)

Early detection of folate receptor autoantibodies is crucial, as these antibodies are linked to conditions like Cerebral Folate Deficiency, Autism Spectrum Disorders, and other neurodevelopmental challenges. FRAT® is the only test that identifies both blocking and binding autoantibodies, backed by leading clinical research. When identified early, personalized treatment — such as reduced folate supplementation and dietary adjustments — may help improve neurological development and long-term outcomes. All results and treatment decisions should be guided by a qualified healthcare professional.

how it works

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Visit or We’ll Visit You: Start your journey either by visiting our clinic or opting for our convenient home collection service.

FDA Approved Laboratory

Global Laboratory Analysis: Your sample is sent to one of the world’s leading laboratories, ensuring top-notch accuracy and reliability.

Personalized Health Plan

Comprehensive Insights: Within 10 days, receive your detailed genetic report and Free Consultation. Your path to personalized health insights begins here.

About FRAT Test

Who Should Consider FRAT.

  • Children with developmental delays or autism concerns
    Early identification of folate receptor autoantibodies may help uncover a treatable underlying factor affecting learning, behavior, and brain development.

  • Pregnant women or those planning pregnancy
    Ensuring proper folate transport to the brain and developing nervous system may reduce the risk of neurodevelopmental complications.

  • Individuals with unexplained neurological or behavioral symptoms
    Symptoms such as cognitive decline, mood disorders, or chronic fatigue may be influenced by impaired folate access to the brain.

Benefits of Early Detection

  • Guides personalized treatment strategies
    Knowing whether folate receptor autoantibodies are present allows healthcare providers to tailor interventions such as targeted folate therapies and dietary changes.

  • Supports better developmental outcomes
    When folate reaches the brain effectively, it may help improve learning, behavior, focus, and overall neurological function — especially during early childhood development.

  • Enables early nutritional and medical intervention
    Starting treatment sooner can help reduce the potential long-term impact of folate transport issues, giving individuals the best chance for optimal progress.

When Should You Consider Testing?

  • Testing is especially important:

    • As soon as developmental concerns arise in young children

    • Before or during pregnancy to support healthy fetal development

    • When neurological or behavioral symptoms have no clear cause

    • If there is a known history of folate-related issues in the family

    Early testing means earlier action — and the potential for better outcomes.

getchecked Clinic

Unparalleled specificity and sensitivity. This test measures:

Levels of homocysteine, folate, and vitamin B12— key biomarkers involved in methylation

Single nucleotide polymorphisms— genetic variations that can affect methylations

Validated and accredited. Science-backed testing and analysis based on rigorous, ongoing research by clinical experts.

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