FRAT Test - Advanced Early Detection for Brain Folate Issues
The Folate Receptor Autoantibody Test (FRAT) is a breakthrough blood test that identifies autoantibodies which block the transport of folate (Vitamin B9) to the brain. When detected early, families and healthcare providers can take action that may help support better neurological development and long-term brain health.
Sample Type
What's included
- Free Consultation with Wellness Doctor
- comprehensive personalized report
- Tested in world’s best Laboratories
- Fast reporting time

The Folate Receptor Autoantibody Test (FRAT)
Early detection of folate receptor autoantibodies is crucial, as these antibodies are linked to conditions like Cerebral Folate Deficiency, Autism Spectrum Disorders, and other neurodevelopmental challenges. FRAT® is the only test that identifies both blocking and binding autoantibodies, backed by leading clinical research. When identified early, personalized treatment — such as reduced folate supplementation and dietary adjustments — may help improve neurological development and long-term outcomes. All results and treatment decisions should be guided by a qualified healthcare professional.
- Autism Spectrum Disorder (ASD)
- Developmental delays
- Cerebral Folate Deficiency
- Learning and behavioral challenges
- Neuropsychiatric symptoms such as mood changes

how it works
Book in Clinic or Home
FDA Approved Laboratory
Personalized Health Plan
About FRAT Test
Who Should Consider FRAT.
Children with developmental delays or autism concerns
Early identification of folate receptor autoantibodies may help uncover a treatable underlying factor affecting learning, behavior, and brain development.Pregnant women or those planning pregnancy
Ensuring proper folate transport to the brain and developing nervous system may reduce the risk of neurodevelopmental complications.Individuals with unexplained neurological or behavioral symptoms
Symptoms such as cognitive decline, mood disorders, or chronic fatigue may be influenced by impaired folate access to the brain.
Benefits of Early Detection
- Guides personalized treatment strategies
Knowing whether folate receptor autoantibodies are present allows healthcare providers to tailor interventions such as targeted folate therapies and dietary changes.
- Supports better developmental outcomes
When folate reaches the brain effectively, it may help improve learning, behavior, focus, and overall neurological function — especially during early childhood development.
- Enables early nutritional and medical intervention
Starting treatment sooner can help reduce the potential long-term impact of folate transport issues, giving individuals the best chance for optimal progress.
When Should You Consider Testing?
Testing is especially important:
As soon as developmental concerns arise in young children
Before or during pregnancy to support healthy fetal development
When neurological or behavioral symptoms have no clear cause
If there is a known history of folate-related issues in the family
Early testing means earlier action — and the potential for better outcomes.

